155 Results for "

Piper nigrum Linn.

" in MedChemExpress (MCE) Product Catalog:
Products (155)

155 Results for "Piper nigrum Linn." in MCE Product Catalog:

53
Silvestrol
Silvestrol
0 Images
53 Publications Verification
Cat. No.: HY-13251
CAS No.: 697235-38-4
Purity:  99.96%
Synonyms: (-)-Silvestrol
Category:  

Agave americana Linn. Natural Products Agavaceae Plants Disease Research Fields Cancer

Target:  

Eukaryotic Initiation Factor (eIF) Apoptosis Autophagy

Silvestrol is a eukaryotic translation initiation factor 4A (eIF4A) inhibitor isolated from Agave americana Linn.. Silvestrol induces autophagy and caspase-mediated apoptosis .
14
Morusin
Morusin
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14 Cited Publications
Cat. No.: HY-N0622
CAS No.: 62596-29-6
Synonyms: Mulberrochromene
Category:  

Anti-aging Flavones Plants Infection other families Flavonoids Phenols Polyphenols Disease Research Fields Inflammation/Immunology

Target:  

NF-κB STAT Bacterial

Morusin is a prenylated flavonoid isolated from Morus alba Linn. with various biological activities, such as antitumor, antioxidant, and anti-bacteria property. Morusin could inhibit NF-κB and STAT3 activity.
12
Vitexin
Vitexin
0 Images
12 Cited Publications
Cat. No.: HY-N0013
CAS No.: 3681-93-4
Category:  

Cardiovascular Disease Neurological Disease Anti-aging Flavones Metabolic Disease Plants Flavonoids Leguminosae Phenols Polyphenols Disease Research Fields Trigonella foenum-graecum Linn. Cancer

Target:  

Autophagy

Vitexin is a c-glycosylated flavone, and is found in various medicinal plants species such as Trigonella foenum-graecum Linn. Vitexin has a wide range of pharmacological effects, including anti-oxidant, anti-cancer, anti-inflammatory, anti-hyperalgesic, and neuroprotective effects .
11
Hematoxylin
Hematoxylin
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11 Cited Publications
Cat. No.: HY-N0116
CAS No.: 517-28-2
Synonyms: Natural Black 1; Haematoxylin
Category:  

Leguminosae Caesalpinia sappan L. Other Diseases Phenols Polyphenols Plants Disease Research Fields

Target:  

Amyloid-β

Hematoxylin (Natural Black 1), a naturally occurring flavonoid compound derived from Caesalpinia sappan Linn.. Hematoxylin is a nuclear stain in histology and is also a potent Aβ42 fibrillogenesis inhibitor with an IC50 of 1.6 μM.
10
Isobavachalcone
Isobavachalcone
0 Images
10 Cited Publications
Cat. No.: HY-13065
CAS No.: 20784-50-3
Purity:  99.01%
Synonyms: Corylifolinin; Isobacachalcone
Category:  

Plants Flavonoids Chalcones Leguminosae Phenols Polyphenols Psoralea corylifolia L. Disease Research Fields Glycyrrhiza uralensis Fisch. Cancer

Target:  

Akt Reactive Oxygen Species (ROS) Apoptosis Autophagy

Isobavachalcone (Corylifolinin) is derived from Psoralea corylifolia Linn. and is a potent inhibitor of Akt signaling pathway, which induces apoptosis in human cancer cells (Inhibits OVCAR-8 cell growth with an IC50 value of 7.92 μM). Isobavachalcone also induces Reactive Oxyen Species (ROS) generation in OVCAR-8 cells and has exhibit cancer anti-promotive and anti-proliferative activity .
4
Asparagusic acid
Asparagusic acid
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4 Cited Publications
Cat. No.: HY-50730
CAS No.: 2224-02-4
Category:  

Infection Liliaceae Ketones, Aldehydes, Acids Plants Disease Research Fields Asparagus officinalis L.

Target:  

Parasite Endogenous Metabolite

Asparagusic acid is a sulfur-containing flavor component produced by Asparagus officinalis Linn., with anti-parasitic effect. Asparagusic acid is a plant growth inhibitor .
3
α-Solanine
α-Solanine
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3 Cited Publications
Cat. No.: HY-N6602
CAS No.: 20562-02-1
Category:  

Solanum nigrum Linn. Plants Solanaceae Disease Research Fields Cancer Steroids

Target:  

Apoptosis Autophagy Akt mTOR MMP NO Synthase COX NF-κB

α-solanine, a bioactive component and one of the major steroidal glycoalkaloids in Solanum nigrum, has been observed to inhibit growth and induce apoptosis in cancer cells .
3
Jervine
Jervine
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3 Cited Publications
Cat. No.: HY-N0836
CAS No.: 469-59-0
Synonyms: 11-Ketocyclopamine
Category:  

Alkaloids Piperidine Alkaloids Veratrum nigrum Linn. Liliaceae Plants Disease Research Fields Inflammation/Immunology

Target:  

Hedgehog Smo

Jervine (11-Ketocyclopamine) is a potent Hedgehog (Hh) inhibitor with an IC50 of 500-700 nM . Jervine is a natural teratogenic sterodial alkaloid from rhizomes of Veratrum nigrum. Jervine has anti-inflammatory and antioxidant properties .
3
Khasianine
Khasianine
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3 Cited Publications
Cat. No.: HY-N2322
CAS No.: 32449-98-2
Category:  

Alkaloids Piperidine Alkaloids Solanum nigrum Linn. Plants Solanaceae Disease Research Fields Cancer

Target:  

Others

Khasianine is a steroidal glycoalkaloid which is obtained from black nightshade (Solanum Nigrum L.), which displays antitumor activity.
3
Aurantiamide acetate
Aurantiamide acetate
0 Images
3 Cited Publications
Cat. No.: HY-N2905
CAS No.: 56121-42-7
Synonyms: Asperglaucide
Category:  

Natural Products Portulacaceae Plants Portulaca oleracea Linn. Disease Research Fields Inflammation/Immunology

Target:  

Cathepsin

Aurantiamide acetate (TMC-58A) is a selective and orally active cathepsin inhibitor isolated from Portulaca oleracea L. Aurantiamide acetate has anti-inflammatory activities and can be used for the study of inflammatory diseases .
2
Methyl vanillate
Methyl vanillate
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2 Cited Publications
Cat. No.: HY-75342
CAS No.: 3943-74-6
Category:  

Microorganisms Monophenols Oryza sativa Linn. Gramineae Phenols Plants

Target:  

Wnt Reactive Oxygen Species (ROS) Endogenous Metabolite

Methyl vanillate, one of the ingredients in Oryza sativa Linn., is a Wnt/β-catenin pathway activator . A benzoate ester that is the methyl ester of vanillic acid. It has a role as an antioxidant and a plant metabolite.
2
Kavain
Kavain
0 Images
2 Cited Publications
Cat. No.: HY-N2096
CAS No.: 3155-48-4
Category:  

Natural Products Piperaceae Piper methysticum G.Forst. Plants

Target:  

GABA Receptor

Kavain is a class of kavalactone isolated from Piper methysticum, which has anxiolytic properties in animals and humans. Kavain positively modulated γ-Aminobutyric acid type A (GABAA) receptor .
2
Moracin O
Moracin O
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2 Cited Publications
Cat. No.: HY-N3244
CAS No.: 123702-97-6
Category:  

Neurological Disease Phenols Polyphenols Plants Moraceae Disease Research Fields Inflammation/Immunology Morus alba Linn.

Target:  

HIF/HIF Prolyl-Hydroxylase Reactive Oxygen Species (ROS)

Moracin O is a 2-arylbenzofuran isolated from the Morus alba Linn. . Moracin O exhibits potent in vitro inhibitory activity against hypoxia-inducible factor (HIF-1). Moracin O reduces oxygen-glucose deprivation (OGD)-induced reactive oxygen species (ROS) production. Moracin O has neuroprotective and anti-inflammatory effects .
1
Piperlonguminine
Piperlonguminine
0 Images
1 Cited Publications
Cat. No.: HY-126562
CAS No.: 5950-12-9
Purity:  99.31%
Category:  

Cardiovascular Disease Infection Alkaloids Capsicum annuum L. Neurological Disease Plants Solanaceae Disease Research Fields Inflammation/Immunology

Target:  

Bacterial Fungal Antibiotic

Piperlonguminine is an alkaloid amide isolated from the Piper species. Piperlonguminine shows various biological properties, including anti-inflammatory, antitumor, neuroprotective, anti-platelet, anti-melanogenic, antifungal and antibacterial activities .
1
Arnidiol
Arnidiol
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1 Cited Publications
Cat. No.: HY-N4165
CAS No.: 6750-30-7
Category:  

Triterpenes Terpenoids Dendranthema morifolium (Ramat.) Tzvel. Other Diseases Plants Compositae Disease Research Fields

Target:  

Others

Arnidiol is a pentacyclic triterpene isolated from Barleria Longiflora Linn F. .
1
3-Epioleanolic acid
3-Epioleanolic acid
0 Images
1 Cited Publications
Cat. No.: HY-N4290
CAS No.: 25499-90-5
Category:  

Triterpenes other families Terpenoids Plants Disease Research Fields Inflammation/Immunology

Target:  

Others

3-Epioleanolic acid is an active component of Verbena officinalis Linn, with anti-inflammatory activity .
1
Vitexin (Standard)
Vitexin (Standard)
0 Images
1 Cited Publications
Cat. No.: HY-N0013R
CAS No.: 3681-93-4
Category:  

Flavonoids Leguminosae Flavones Phenols Polyphenols Plants Trigonella foenum-graecum Linn.

Target:  

Reference Standards Autophagy

Vitexin (Standard) is the analytical standard of Vitexin. This product is intended for research and analytical applications. Vitexin is a c-glycosylated flavone, and is found in various medicinal plants species such as Trigonella foenum-graecum Linn. Vitexin has a wide range of pharmacological effects, including anti-oxidant, anti-cancer, anti-inflammatory, anti-hyperalgesic, and neuroprotective effects .
1
4-Allylcatechol
4-Allylcatechol
0 Images
1 Cited Publications
Cat. No.: HY-N1887
CAS No.: 1126-61-0
Synonyms: Hydroxychavicol; 4-Allylpyrocatechol
Category:  

Ophiopogon japonicus (L. f.) Ker-Gawl. Liliaceae Other Diseases Phenols Polyphenols Plants Disease Research Fields

Target:  

Bacterial Antibiotic TNF Receptor Interleukin Related

4-Allylcatechol (4-Allylpyrocatechol) is a xylan which has oral activity and can be isolated from the root of Piper taiwanense. 4-Allylcatechol has a strong inhibitory activity against collagen-induced platelet aggregation (IC50 = 5.3 μM). In addition, 4-Allylcatechol has anti-tuberculosis activity against Mycobacterium tuberculosis H37Rv (MIC = 27.6 μg/mL) .
1
Delphinidin 3-rutinoside chloride
Delphinidin 3-rutinoside chloride
0 Images
1 Cited Publications
Cat. No.: HY-114367
CAS No.: 15674-58-5
Purity:  98.83%
Synonyms: Delphinidin 3-O-rutinoside chloride
Category:  

Anthocyans Flavonoids Solanum melongena L. Phenols Polyphenols Plants Solanaceae Disease Research Fields Cancer

Target:  

Endothelin Receptor NO Synthase Myosin GLP Receptor

Delphinidin 3-rutinoside chloride is an anthocyanin component. Delphinidin 3-rutinoside chloride is isolable from the fruits of blackcurrant Ribes nigrum L. Delphinidin 3-rutinoside chloride activates the ETB receptor and stimulates the NO/cGMP pathway. Delphinidin 3-rutinoside chloride increases cyclic guanosine monophosphate production and reduces the phosphorylation level of Myosin regulatory light chain. Delphinidin 3-rutinoside chloride stimulates GLP-1 secretion. It significantly induces relaxation of bovine ciliary muscle strips contracted by ET-1 and inhibits ET-1-induced contraction of bovine ciliary muscle strips. Delphinidin 3-rutinoside chloride is applicable to research related to type 2 diabetes .
Protodioscin
Protodioscin
0 Images
Cat. No.: HY-N0799
CAS No.: 55056-80-9
Category:  

Leguminosae Plants Endogenous metabolite Disease Research Fields Trigonella foenum-graecum Linn. Cancer Steroids

Target:  

Endogenous Metabolite

Protodioscin, a major steroidal saponin in Trigonella foenum-graecum Linn., has been shown to exhibit multiple biological actions, such as anti-hyperlipidemia, anti-cancer, sexual effects and cardiovascular properties.
Assay Types